Center for Integrative Toxicology at Michigan State University

Aaron Fullerton

Picture of Environmental and Integrative Toxicological Sciences trainee at Michigan State UniversityCooperating Doctoral Program: Pharmacology and Toxicology

EITS Track: Toxicology

Education: B.S., Biology, Alma College

Research Interests:
My research goals involve the investigation of how exposure to aryl hydrocarbon recptor ligands can lead to hepatic toxicity. Specifically, I am researching the mechanism through which a subtoxic dose of the environmental contaminant 2,3,7,8 tetrachiorodibenzo-p-dioxin (TCDD) can interact in a synergistic manner with a subsequent inflammatory response initiated by the administration of lipopolysaccharide (LPS) to result in liver injury. I will attempt to determine the mechanisms through which TCDD is able to interact with the signal transduction pathways utilized by LPS to modulate the production and release of inflammatory cytokines, alter immune cell activity, and affect other biological responses commonly associated with inflammation.

Major Professor: Robert Roth, Pharmacology and Toxicology

Contact: fuller22@msu.edu