Topics in Particle Toxicology:
From micro- to nano-particles
Sponsored by the Michigan State University
Center for Integrative Toxicology and the
Department of Pathobiology and Diagnostic Investigation
Course Description: Historically, research in particle toxicology has been closely connected to industrial exposures to coal, asbestos, and synthetic fibers. More recently, research has focused on the toxicology of ambient particulate matter and man-made nanoparticles. In this course, students will review research literature related to the adverse human health and environmental effects of occupational and environmental exposures to a wide-range of particles varying in size (microns to nanometers in diameter) and chemical composition. Though most of the reviewed areas of research will concern inhalation exposures and pulmonary toxicity, other routes of exposure (e.g., oral, dermal) and particle-induced effects on other target organs (e.g., cardiovascular) will be discussed. The goal of this course is to provide students will an introduction to particle toxicology concentrating on topics related to particulate exposure, dosimetry (deposition and clearance), cellular responses, and pathological outcomes. In addition, students will gain an understanding of in vivo and in vitro models and methods for toxicological testing of particles.
Course Title: Topics in Particle Toxicology: From micro- to nano-particles
Term: Summer semester 2008 (first term only ¾ May 12-June 26, 2008)
Class time: Wednesdays, 1:00 – 3:00 pm
Location: Conference room 162, National Food Safety and Toxicology Bldg.
Course Number: PDI 891
Course Credit: 1
Enrollment: Students must contact Ms. Denise Harrison in the Department of Pathobiology and Diagnostic Investigation (517- 432-4685 or harrison@dcpah.msu.edu) with a student number and course title to receive an override in order to enroll.
Course moderators: Drs. Jack Harkema (PDI) and Patricia Ganey (PHM/TOX)
4/2/08